Subgroups1 Medulloblastoma Subgroups and the Role of WNT signaling Mutations in CTNNB1 and APC Genes Explore the classification of Medulloblastoma into four subgroups and understand the impact of CTNNB1 and APC gene mutations driving constitutive WNT signaling in the context. Medulloblastoma Subtypes: Wnt Signaling Mutaions in CTNNB1 and APC genes We know that Medulloblastoma was divided into four subgroups: WNT, SHH, Group3, and Group4. In the context of molecular mutations, the somatic CTNNB1.. 2023. 4. 6. 이전 1 다음